Total-Body Irradiation, Cyclophosphamide, and Stem Cell Transplantation in Treating Patients With Hematologic Cancer
Status:
Completed
Trial end date:
2004-07-01
Target enrollment:
Participant gender:
Summary
RATIONALE: Adjusting the dose of drugs used in chemotherapy such as cyclophosphamide may
decrease side effects while stopping cancer cells from dividing so they stop growing or die.
Radiation therapy uses high-energy x-rays to damage cancer cells. Stem cell transplantation
may be able to replace immune cells that were destroyed by chemotherapy and radiation therapy
used to kill cancer cells.
PURPOSE: Phase I trial to study the effect on the body of dose-adjusted cyclophosphamide
combined with total-body irradiation and donor stem cell transplantation in treating patients
who have hematologic cancer.