Overview

Total Body Irradiation +/- Total Lymphoid Irradiation & Anti-Thymocyte Globulin in Non-myeloablative Hematopoietic Cell Transplantation

Status:
Completed

Trial end date:
2020-11-17

Target enrollment:

Participant gender:

Summary

The purpose of this study is to evaluate whether addition of a low dose of total body irradiation (TBI) to a standard preparation for transplant [total lymphoid irradiation (TLI) and anti-thymocyte globulin (ATG)] conditioning will help to augment donor chimerism without reducing tolerability of this regimen or increasing the risk of graft-vs-host disease (GVHD)

Phase:

Phase 2

Details

Lead Sponsor:

Stanford University

Treatments:

Antilymphocyte Serum
Mycophenolic Acid
Tacrolimus