Total Post-thyroidectomy Hypocalcemia After Preoperative Cholecalciferol Supplementation

• Status: Recruiting
• Trial end date: 2024-03-01
• Target enrollment: 0
• Participant gender: All

Summary

This prospective study evalue the inflence of pre operative vit D3 administration on post operative hypocalcemia in patients undergoing Total thyroidectomy

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Centre Hospitalier René Dubos
• Treatments: Vitamin D

Criteria

Inclusion Criteria:

• Patient ≥ 18 years old

• Patient shall be operated on for a total thyroidectomy in one time for any indication

• Written informed consent (IC) obtained

• Patients with affiliation to the social security system

Exclusion Criteria:

• Medical history of : Thyroid or parathyroid surgery Hyperparathyroidism Granulomatosis flare-up

• Hypocalcemia, hypercalcemia/ hypercalciuria, or symptom of Hypocalcemia, hypercalcemia/ hypercalciuria, not due to thyroid pathologies

• Chronic kidney disease grade ≥4

• Severe liver failure

• 25OHD supplementation within last 3 months before surgery

• Malabsorption syndrome

• Known hypersensitivity to vitamin D

• Medical history of calcic lithiasis

• Pregnant women

• Vulnerable populations (guardianship or trusteeship)