Towards a Wearable Alcohol Biosensor: Examining the Accuracy of BAC Estimates From New-Generation Transdermal Technology Using Large-Scale Human Testing and Machine Learning Algorithms

• Status: Recruiting
• Trial end date: 2027-09-01
• Target enrollment: 0
• Participant gender: All

Summary

The study will employ a combined laboratory-ambulatory design. Participants will engage in ambulatory assessment over the course of 14 days, wearing biosensors assessing transdermal alcohol concentration (TAC) and providing breathalyzer readings in real-world contexts. Also during this period, participants will attend three laboratory alcohol-administration sessions scheduled at one-week intervals, with alcohol dose and rate of consumption manipulated within and between participants, respectively. Laboratory visits will also double as ambulatory orientation, check-in, and close-out sessions.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: University of Illinois at Urbana-Champaign
• Collaborator: National Institutes of Health (NIH)

Criteria

Inclusion Criteria:

• 21 years or older

• drink alcohol at least 2x weekly

Exclusion Criteria:

• psychological or medical conditions that might contraindicate alcohol-administration

• history of adverse reaction to type and amount of beverage used in the study

• currently seeking treatment for alcohol use disorder

• does not drink alcohol regularly

• taking drugs or medications for which alcohol consumption would be contraindicated

• women who are pregnant or are attempting to become pregnant