Overview

Toxicogenomic and Immunocytotoxic Effects of Propofol and Isoflurane Anesthetics in Patients Undergoing Elective Surgery

Status:
Completed
Trial end date:
2009-12-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to evaluate if the anesthetics propofol and isoflurane can damage DNA, induce apoptosis, change expression of genes related to apoptosis and DNA repair and change cytokines profile in patients submitted to elective surgery.
Phase:
Phase 4
Details
Lead Sponsor:
UPECLIN HC FM Botucatu Unesp
Collaborator:
Fundação de Amparo à Pesquisa do Estado de São Paulo
Treatments:
Anesthetics
Isoflurane
Propofol