Tracheobronchitis Prevention Trial

• Status: Completed
• Trial end date: 2013-05-01
• Target enrollment: 0
• Participant gender: All

Summary

We aim to study whether the use of inhaled antibiotics may have an impact on the incidence of tracheobronchitis and pneumonia associated with the use of mechanical ventilation. The investigators hypothesize that this could be possible by decreasing the population of gram negative germs that colonize the lumen of tracheal tube and upper airways.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of Thessaly
• Treatments: Colistin

Criteria

Inclusion Criteria:

• All intubated and tracheostomized patients, older than 18 years old with duration of intubation of 48 hours.

Exclusion Criteria:

• Purulent sputum within 48 hours from admission

• Pneumonia within 48 hours of intubation

• New chest X ray infiltrate

• Advanced COPD that led to intubation

• Pregnancy

• Allergy to colistin

• Resistance of the bacterial strain to colistin