Overview
Traditional Chinese Medicine (TCM) Colon Dialysis Treats Non-dialysis End-Stage Kidney Disease
Status:
Unknown status
Unknown status
Trial end date:
2018-10-15
2018-10-15
Target enrollment:
0
0
Participant gender:
All
All
Summary
This study evaluates the clinical efficacy and study the therapeutic mechanism of a kind of traditional Chinese medicine colonic dialysis on Chronic kidney disease (CKD) 5 without blood dialysis therapy in adults. Half of participants will receive conventional integrated therapy on chronic renal failure (CRF), while the other half will receive integrated therapy on CRF and traditional Chinese medicine colonic dialysis.Phase:
Phase 1/Phase 2Accepts Healthy Volunteers?
NoDetails
Lead Sponsor:
Pang PengCollaborator:
Guangdong Provincial Hospital of Traditional Chinese Medicine
Criteria
Inclusion Criteria:- 1.corresponding to diagnosis standards of CKD-5:eGFR≤15ml/min/1.73m2; 2. did not
receive kidney replacement therapy; 3. no gastrointestinal diseases (including
ulcerative colitis, irritable bowel syndrome, inflammation, cancer, infection,
bleeding, etc.) in the past 1 year; 4.not associated with rectal-related disorders
(hemorrhoids, anal fistula, rectal cancer, cancer, infection, bleeding, etc.); 5.Sign
informed consent.
Exclusion Criteria:
- 1. having used antibiotics, hormones, immunosuppressive, probiotics and laxatives in
past three months; 2. pregnant or lactating patients; 3.cannot cooperate or tolerate
colonic dialysis treatment; 4.combined with active stage of malignant tumors,
cardiovascular, respiratory system, decompensated liver cirrhosis or blood system
diseases (including coagulation disorders, hematopoietic dysfunction, etc.) and other
serious primary disease; 5. recent merger of patients with infectious diseases;
6.having known to be allergic to some drugs in the study.