Training the Innate Immune System Against SARS-CoV-2 (COVID-19) Using the Shingrix Vaccine in Nursing Home Residents
Status:
Recruiting
Trial end date:
2021-12-30
Target enrollment:
Participant gender:
Summary
The purpose of this study is to measure the effect of the Shingrix vaccine on your immune
system and whether that has any effect on the body's ability to fight off other infections
such as COVID-19. We hypothesize that:
H1: Shingrix vaccination will elevate acute and trained immunity
H2: For 6 months following the first injection, increased levels of acute and trained
immunity is associated with less disease, including fewer hospitalizations and deaths
associated with flu, pneumonia, and COVID-19.