Tramadol Versus Celecoxib for Reducing Pain During Office Hysteroscopy in Post Menopausal Women
Status:
Unknown status
Trial end date:
1969-12-31
Target enrollment:
Participant gender:
Summary
Two hundreds and twenty five postmenopausal women undergoing outpatient hysteroscopy and
endometrial biopsy will be randomly divided into three equal groups. To ensure blinding the
investigators will use the double dummy technique in which group 1 will receive Tramadol
100mg (Trama®, Global Napi, Giza, Egypt) orally in addition to a placebo similar to
Celecoxib, group 2 will receive Celecoxib 200mg (Celebrex® 200, Pfizer, USA) in addition to a
placebo similar to Tramadol, and group 3 will received a placebo similar to Tramadol and a
placebo similar to Celecoxib. All drugs will be given 2 hours before the procedure. An
independent person will generate the allocation sequence using computer generated random
numbers.
Patient's perception of pain will be assessed for each group during the procedure,
immediately after and 30 min after the procedure with the use of visual analogue scale (VAS).