Tramadol and Pain Sensitization

• Status: Completed
• Trial end date: 2008-03-01
• Target enrollment: 0
• Participant gender: Male

Summary

Tramadol is a largely used analgesic drug. Its role however on sensitization as occurs for example in neuropathic pain is not very well known. This protocol aims therefore at studying the effect of tramadol in a human pain model with sensitization induced by a cold stimulus, using evoked potentials to elucidate how pain is modified when tramadol is administered.

• Phase: Phase 1
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: University Hospital, Clermont-Ferrand
• Treatments: Tramadol

Criteria

Inclusion Criteria:

• Healthy men

• Between 18 and 40 years old

• Written consent given

Exclusion Criteria:

• Concomitant medication

• Tramadol hypersensibility

• Excessive consumption of alcohol, tobacco, coffee, tea or toxicomania