Tramadol iv. : Influence of Dose and Dose Intervals on Therapeutic Accuracy and Side Effects When Used for Postoperative Pain Relief in Ambulatory Surgery

• Status: Completed
• Trial end date: 2009-04-01
• Target enrollment: 0
• Participant gender: All

Summary

The aim of this study is to compare the administration of 1 unit dose of 100 mg tramadol intravenously versus multiple smaller dosages of tramadol during the first 6 hours post-operatively and to investigate the time course and accuracy of pain relief versus the onset and duration of side-effects.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University Hospital, Ghent
• Treatments: Tramadol

Criteria

Inclusion Criteria:

• ASA I and II female or male patients

• Aged 18-70 years

• Scheduled for ambulatory surgery requiring postoperative pain medication.

Exclusion Criteria:

• Weight less than 70% or more than 130% of ideal body weight

• Neurological disorder

• Recent use of psycho-active medication, including alcohol

• Patients suffering from chronic pain receiving pre-operative pain medication including NSAID's

• Use of chronic anti-emetic medication, use of chronic corticoid therapy