Tranexamic Acid During Telescoping Nail Application In Osteogenesis Imperfecta

• Status: Not yet recruiting
• Trial end date: 2023-05-01
• Target enrollment: 0
• Participant gender: All

Summary

The aim of this study is to assess the effective of intraoperative use of tranexamic acid in reducing blood loss during telescoping nail application in cases of osteogenesis imperfecta.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Assiut University
• Treatments: Tranexamic Acid

Criteria

Inclusion Criteria:

All patients with osteogenesis imperfecta who will undergo telescoping femoral nail application in Assiut University Hospital - Department of Orthopaedic and Trauma Surgery between April 2022 and March 2023.

Exclusion Criteria:

• Known allergy to Tranexamic Acid

• History of any acquired disturbances of colour vision

• History of major comorbidities (e.g., severe ischemic heart disease)

• Refusal of blood products

• History of fibrinolytic disorders requiring intraoperative antifibrinolytic treatment, coagulopathy in the past and/or as identified by a preoperative platelet count of <150,000/mm3, or a prolonged partial thromboplastin time, active intravascular clotting & known congenital thrombophilia

• Preoperative use of anticoagulant therapy within five days before surgery

• Medical Unfit

• Participation in another clinical trial involving pharmaceutical drugs.

• Patients or their relatives who refuse to participate in the study