Overview
Tranexamic Acid Effect on Digit Function Following Primary Repair of Traumatic Digit Flexor Tendon Injuries
Status:
Not yet recruiting
Not yet recruiting
Trial end date:
2023-03-01
2023-03-01
Target enrollment:
0
0
Participant gender:
All
All
Summary
This study evaluates the effect of pre-operative treatment with IV Tranexamic Acid on post-operative digit function, in patients that underwent surgical repair of traumatic zone 1 or zone 2 digit flexor tendon tear.Phase:
Early Phase 1Accepts Healthy Volunteers?
Accepts Healthy VolunteersDetails
Lead Sponsor:
Rabin Medical CenterTreatments:
Tranexamic Acid
Criteria
Inclusion Criteria:- Patients that will undergo surgical repair of traumatic zone 1 or zone 2 digit flexor
tendon tears
Exclusion Criteria:
- Age < 18
- Pregnant Women
- Patients that presented 3 weeks or later after the injury
- Medical history positive for Rheumatic disease
- Current active treatment with anti-coagulation medications
- Injury to more than one finger
- Presence of a fracture in the affected finger
- Presence of a nerve injury in the affected finger that won't enable early use and
activation in early rehabilitation protocol
- Mangled extremity injury, degloving injury or other soft tissue injuries that won't
enable primary closure of skin
- Previous tear of the affected tendon
- Degenerative tear of flexor tendon
- Tendon tear secondary to infection
- Previous injuries to contralateral side causing dysfunction and/or decreased fingers'
range of motion
- Contraindications to Tranexamic acid treatment:
- Known hypersensitivity to tranexamic acid or to any other ingredient of the
preparation.
- Patients with thromboembolic disease.
- Patients with active intravascular clotting.
- Severe renal failure because of risk of accumulation.
- Patients with subarachnoid hemorrhage
- Patients with acquired defective color vision