Tranexamic Acid Infusion During Elective Spine Surgery

• Status: Enrolling by invitation
• Trial end date: 2021-01-01
• Target enrollment: 0
• Participant gender: All

Summary

Tranexamic acid (TXA) is an agent that has been shown to be safe and effective to reduce blood loss in surgical procedures. The purpose of the study is to assess the effect of transexamic on elective decompressive lumbar spine surgery with and without fusion.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Albany Medical College
• Treatments: Tranexamic Acid

Criteria

Inclusion Criteria:

• Patients undergoing decompressive lumbar laminectomy with or without fusion

• Primary surgical procedure

• Competent adult able to give informed consent

• Age >18

Exclusion Criteria:

• h/o DVT or PE

• h/o seizure

• h/o coagulopathy

• Diagnosis of malignancy or infection as indication for surgical decompression

• Abnormal pre-operative PT/INR, aPTT, bleeding time

• Platelet count < 100

• Patients requiring therapeutic heparin or lovenox bridges prior to and/or after surgery

• Allergy to TXA

• Pregnant women and prisoners

• Renal insufficiency