Tranexamic Acid Study

• Status: Withdrawn
• Trial end date: 2008-01-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to determine if tranexamic acid significantly reduces blood loss and blood transfusion in revision total hip replacement. Tranexamic acid is a drug that helps to reduce blood loss during surgery. Revision total hip replacement surgery is treatment for patients who have previously had hipe replacement surgery which failed and must be repaired/replaced.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Texas Tech University Health Sciences Center
• Treatments: Tranexamic Acid

Criteria

Inclusion Criteria:

• Failed primary total hip arthroplasty (femoral stem, acetabular component, or both)

• 18-100 years of age

Exclusion Criteria:

• Prosthetic infection

• Primary total hip arthroplasty

• Prisoners

• Pregnancy

• Previous adverse reaction to tranexamic acid

• Bleeding/coagulation disorders

• Renal insufficiency (serum creatinine>two standard deviations for age)

• History of deep venous thrombosis or pulmonary embolism

• Religious beliefs/practices prohibiting blood transfusions

• Wards of the state

• Cognitively impaired patients

• Terminally ill patients

• Students and/or employees

• Color blindness