Tranexamic Acid (TXA) Versus Epsilon Aminocaproic Acid (EACA) Versus Placebo for Spine Surgery
Status:
Completed
Trial end date:
2012-09-01
Target enrollment:
Participant gender:
Summary
Tranexamic acid (TXA) and epsilon aminocaproic acid (EACA) have been reported to reduce blood
loss in the cardiac surgery literature but they have not been reported in use head-to-head in
the orthopedic surgery literature. In a randomized, double-blind, prospective study we
believe that TXA will be more effective than both EACA and placebo at reducing blood loss for
corrective spinal surgery.