Tranexamic Acid Versus Epinephrine During Exploratory Tympanotomy

• Status: Completed
• Trial end date: 2020-04-10
• Target enrollment: 0
• Participant gender: All

Summary

Exploratory tympanotomy is surgical access to the middle ear, made for diagnosis and management of unexplained conductive hearing loss, performed under an oto-microscope across the external auditory canal after tympanic membrane elevation to explore the middle ear structures

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Assiut University
• Treatments: Epinephrine; Epinephryl borate; Racepinephrine; Tranexamic Acid

Criteria

Inclusion Criteria:

• 18 - 60 years old

• ASA (I and II)

• Hb level > 10 mg/dl

• elective ear exploratory tympanotomy surgery under general anesthesia.

Exclusion Criteria:

• Allergy to TXA

• bleeding/coagulation disorders

• psychiatric illness

• acute and chronic renal failure

• heparin use within 48 hrs or aspirin use within seven days before surgery,

• pregnancy

• liver cirrhosis

• color blindness

• cardiac stent.