Tranexamic Acid and Epistaxis in Hereditary Hemorrhagic Telangiectasia (HHT)
Status:
Completed
Trial end date:
2002-10-01
Target enrollment:
Participant gender:
Summary
Hereditary hemorrhagic telangiectasia (HHT, Rendu-Osler-Weber Syndrome) is associated with
frequent nosebleeds in the majority of cases. Several reports in the literature support the
use of antifibrinolytics like Tranexamic acid to reduce nosebleeds. The objectives of the
study are to test if Tranexamic acid taken orally can
1. improve anemia (lead to an increased hemoglobin level)
2. reduce nosebleeds.