Tranexamic Acid for Unilateral Total Knee Arthroplasty

• Status: Completed
• Trial end date: 2012-10-01
• Target enrollment: 0
• Participant gender: All

Summary

Total knee arthroplasty is often associated with excessive postoperative bleeding due to increased fibrinolysis. Hence, the objective of the proposed of this multicentre study is to determine the peri-operative bleeding comparing the application of topical and intravenous tranexamic acid with the habitual surgical haemostasis.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
• Treatments: Tranexamic Acid

Criteria

Inclusion Criteria:

• Unilateral Total knee arthroplasty

• The patient consent to participate

Exclusion Criteria:

• Antecedent of thromboembolic disease

• Patient with cardiac alterations of the rhythm

• Patients with valvular cardiac prosthesis

• Patients with pro-thrombotic alterations of coagulation

• Treatment with anticonceptive drugs