Tranexamic Acid in Functional Endoscopic Sinus Surgery

• Status: Recruiting
• Trial end date: 2023-03-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of the study is to compare the effect of oral tranexamic acid vs. intravenous in decreasing bleeding and improving the field during FESS.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Ain Shams University
• Treatments: Tranexamic Acid

Criteria

Inclusion Criteria:

• American Society of Anesthesiologists grade I or II.

• Sex: Both sexes.

• Age between 18 and 40 years.

• Patients scheduled for FESS under general anesthesia.

Exclusion Criteria:

• Declining to give written informed consent.

• History of allergy to the medications used in the study.

• History of venous or arterial thrombosis.

• history of cardiovascular diseases including AF, IHD, or hypertension.

• History of chest problems including pulmonary embolism, bronchial asthma and COPD.

• History of cerebrovascular stroke.

• History of drug or alcohol abuse.

• Taking opioids or sedative medications.

• Hepatic or renal failure.

• Bleeding disorders, antiplatelets (aspirin, clopidogrel) or anticoagulant (warfarin).