Tranexamic Acid in Off-pump Coronary Surgery

• Status: Completed
• Trial end date: 2009-12-01
• Target enrollment: 0
• Participant gender: All

Summary

The aim of this prospective, randomized, double-blinded, placebo-controlled study was to evaluate the effects of tranexamic acid, a synthetic antifibrinolytic drug, on the postoperative bleeding and transfusion requirements in patients undergoing off-pump coronary artery bypass graphing (OPCAB) surgery.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Chinese Academy of Medical Sciences, Fuwai Hospital
• Treatments: Tranexamic Acid

Criteria

Inclusion Criteria:

• Patients for elective offpump coronary artery bypass surgery

Exclusion Criteria:

• A history of bleeding disorders

• Active chronic hepatitis or cirrhosis

• Chronic renal insufficiency (serum creatinine > 2 mg/dL)

• Preoperative anemia (Hb < 10 g/dL)

• Previous cardiac surgery

• Myocardial infarction < 7 days before surgery