Tranexamic Acid's Effects in Patients Undergoing Laparoscopic Radical Prostatectomy

• Status: Not yet recruiting
• Trial end date: 2024-09-01
• Target enrollment: 0
• Participant gender: Male

Summary

The study is randomized, placebo-controlled, double-blind clinical trial that aims to check whether tranexamic acid's use in videolaparoscopic radical prostatectomy intraoperative is effective in decrease serum hemoglobin drop and the amount of blood's transfusion.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Instituto do Cancer do Estado de São Paulo
• Treatments: Tranexamic Acid

Criteria

Inclusion Criteria:

• Patients over 18 years olds;

• Who accept to participate and sign the consent form;

• Compliance with the study follow-up protocol;

• Diagnosed with localized prostate cancer with surgical indication without or with lymphadenectomy.

Exclusion Criteria:

• Coronary artery disease treated with drug-using stent;

• Previous coronary procedures or coronary disease using a stent;

• Acute or chronic liver failure;

• Severe chronic renal failure (ClCr < 30 mL/Kg.h, according to the Modification of Diet in Renal Disease formula);

• Suspected allergy to tranexamic acid;

• Known coagulopathies and refusal to sign consent form.