Overview

Transarterial Chemoembolization With Lipiodol in the Treatment of Initial Unresectable Gastric Cancer (GC)

Status:
Not yet recruiting
Trial end date:
2025-12-01
Target enrollment:
0
Participant gender:
All
Summary
This is a prospective, open-labelled study to evaluate the efficacy and safety of sequential transarterial chemoembolization with lipiodol and neoadjuvant chemotherapy in the treatment of Initial unresectable gastric cancer.
Phase:
Phase 2
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
Gang Wu
Criteria
Inclusion Criteria:

1. Pathological and imaging diagnosis of gastric adenocarcinoma with initial unresectable
R0;

2. Age (18-80 years old) and gender are not limited;

3. No extragastric organ transfer;

4. No serious diseases of the heart, liver, lung, kidney and other organs;

5. Expected survival time > 3 months;

6. Physical performance status score ECOG ≤1 point;

7. Females of reproductive age must have a negative pregnancy test; or male and female
patients must agree to use effective contraception during treatment and within 1 year
thereafter.

Exclusion Criteria:

1. Poor coagulation function, INR>1.5, or ongoing anticoagulation therapy or known
bleeding diseases;

2. WBC <3000/mm3 or platelet count <50000/mm3;

3. AST and/or ALT > 3 times the upper limit of normal;

4. Comorbidities or social environment that can cause subjects to fail to follow the
research plan or even endanger patient safety;

5. The patient has other primary tumors.