Transarterial Chemoembolization for the Treatment of Uveal Melanoma With Liver Metastases
Status:
Recruiting
Trial end date:
2024-09-30
Target enrollment:
Participant gender:
Summary
This phase II trial studies the effect of transarterial chemoembolization in treating
patients with uveal melanoma that has spread to the liver (liver metastases). Transarterial
chemoembolization involves the injection of a blocking agent (gelatin sponge, ethiodized oil)
and a chemotherapy agent (carmustine) directly into the artery in the liver to treat liver
cancers. Chemotherapy drugs, such as carmustine, work in different ways to stop the growth of
tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them
from spreading. transarterial chemoembolization with carmustine in combination with
ethiodized oil and gelatin sponge may help cause the tumors in the liver to shrink or
disappear.