Transcriptome Analysis of the Peripheral Blood in CIDP
Status:
Unknown status
Trial end date:
2018-09-01
Target enrollment:
Participant gender:
Summary
Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is an immune-mediated
disorder of peripheral nerves. Intravenous immunoglobulins (IVIg) are a first line therapy
for CIDP. The investigators used a transcriptomic approach to compare the gene expression
profiles in the peripheral blood of patients having a CIDP or autoimmune diseases, before and
after IVIg treatment, in order to identify their mechanism of action in this condition, to
lead to a better understanding of CIDP pathophysiology, and potentially determine factors
associated with the response to the treatment.