Transdermal Absorption of Dimercaptopropane-1-Sulfonate (DMPS) and Effect on Urinary Mercury Excretion
Status:
Completed
Trial end date:
2010-12-01
Target enrollment:
Participant gender:
Summary
DMPS is a metal chelator which is approved for use in Europe. While not an FDA-approved drug
in the US, it is easily obtained and administered by alternative health practitioners to
their patients. A formulation called 'TD DMPS' (transdermal DMPS) is in use, despite the fact
there is no published literature to support that the agent is absorbed transdermally. The
investigators hypothesis is that DMPS is not absorbed through the skin. The investigators
plan to apply TD DMPS to healthy volunteers and then test serum for presence of DMPS. In
addition the investigators will measure urinary mercury concentrations pre and post DMPS
application.