Overview

Transversus Abdominis Plane Block Versus Wound Infiltration for Analgesia After Cesarean Delivery

Status:
Completed

Trial end date:
2021-08-01

Target enrollment:
0

Participant gender:
Female

Summary

Adequate pain control after cesarean delivery is a major concern both for parturient and for obstetric anesthesiologists, and it usually comprises a combination of systemic and regional techniques.The transversus abdominis plane (TAP) block, affecting the nerves supplying the anterior abdominal wall, is a recently introduced, promising regional analgesic technique for a variety of abdominal and pelvic surgeries including cesarean delivery.(2,3) Infiltration of local anesthetic into the surgical wound (either as a single shot or using indwelling catheters) has long been used for postoperative analgesia. Both the TAP block (4-6) and wound infiltration is superior to placebo; however, it is unknown which of them provides better analgesia after cesarean delivery because of a scarcity of randomized clinical trials. Only 2 studies compared the TAP block with wound infiltration after cesarean delivery with conflicting results, and another study compared it with continuous wound infusion and was prematurely terminated. This study aimed to compare bilateral TAP block with single-shot local anesthetic wound infiltration for analgesia after cesarean delivery performed under spinal anesthesia. We hypothesized that the TAP block would decrease postoperative cumulative opioid consumption at 24 hours

Phase:

N/A

Accepts Healthy Volunteers?

Details

Lead Sponsor:

Aswan University Hospital

Treatments:

Bupivacaine

Criteria

Inclusion Criteria:

- Eligible subjects were American Society of Anesthesiologists physical status I, II
parturient with full-term singleton pregnancies undergoing elective cesarean delivery
under spinal anesthesia

Exclusion Criteria:

- were: <19 years of age or >40 years of age; height <150 cm, weight <60 kg, body mass
index (BMI) >=40 kg/m2; contraindications to spinal anesthesia (increased intracranial
pressure, coagulopathy, or local skin infection); history of recent opioid exposure;
hypersensitivity to any of the drugs used in the study; significant cardiovascular,
renal, or hepatic disease; and known fetal abnormalities