Trastuzumab and External Beam Radiation Therapy in Treating Women With Stage III or Stage IV Breast Cancer
Status:
Completed
Trial end date:
2009-07-01
Target enrollment:
Participant gender:
Summary
RATIONALE: Monoclonal antibodies, such as trastuzumab, can block tumor growth in different
ways. Some block the ability of tumor cells to grow and spread. Others find tumor cells and
help kill them or carry tumor-killing substances to them. Radiation therapy uses high-energy
x-rays to kill tumor cells. Trastuzumab may make tumor cells more sensitive to radiation
therapy. Giving trastuzumab together with radiation therapy may kill more tumor cells.
PURPOSE: This phase II trial is studying the side effects and how well giving trastuzumab
together with external beam radiation therapy works in treating women with stage III or stage
IV breast cancer.