Overview

Traumatic Injury Clinical Trial Evaluating Tranexamic Acid in Children: An Efficacy Study

Status:
Not yet recruiting
Trial end date:
2027-03-31
Target enrollment:
Participant gender:
Summary
Trauma is the leading cause of death and disability in children in the United States. The objective of this study is to evaluate the benefits and harms of tranexamic acid (TXA; a drug that stops bleeding) in severely injured children with hemorrhagic brain and/or torso injuries. Using thromboelastography, we will measure baseline fibrinolysis to assess for treatment effects of TXA at different levels of fibrinolysis.
Phase:
Phase 3
Details
Lead Sponsor:
Daniel Nishijima, MD, MAS
University of California, Davis
Collaborator:
Pediatric Emergency Care Applied Research Network
Treatments:
Tranexamic Acid