Treat Clozapine ( CLZ )-Resistant Schizophrenia Comparing CLZ + Haloperidol vs. CLZ + Electroconvulsive Therapy (ECT)

• Status: Completed
• Trial end date: 2012-05-01
• Target enrollment: 0
• Participant gender: All

Summary

Clozapine treatment resistant schizophrenia is still prevalent.The effectiveness of augmenting clozapine : one augmenting with haloperidol and the other with electroconvulsive therapy should be determined.This study is a randomized control trial.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Khon Kaen University
• Treatments: Clozapine; Haloperidol; Haloperidol decanoate

Criteria

Inclusion Criteria:

1. schizophrenic patients diagnosed with schedules for clinical assessment in neuropsychiatry ( SCAN )in accordance with DSM-IV-TR or ICD-10

2. Resistant to at least 6 weeks of clozapine treatment in therapeutic dosage

3. Voluntary to participate the research protocol expressed by signing informed consent form

Exclusion Criteria:

1. Patient does not volunteer himself or herself

2. Patient is having epilepsy, DM, cardiac disease, autistic disorder and illiterate

3. Patient is deaf, blind , dumb to obstruct good communication