Treating Patients With Prostate Cancer That Did Not Respond to Hormone Therapy
Status:
Completed
Trial end date:
2010-08-31
Target enrollment:
Participant gender:
Summary
RATIONALE: Androgens can cause the growth of prostate cancer cells. Drugs, such as
ketoconazole, may stop the adrenal glands from making androgens. Lenalidomide may stop the
growth of prostate cancer by blocking blood flow to the tumor. Giving ketoconazole and
hydrocortisone together with lenalidomide may be an effective treatment for prostate cancer.
PURPOSE: This phase II trial is studying how well giving ketoconazole and hydrocortisone
together with lenalidomide works in treating patients with prostate cancer that did not
respond to hormone therapy.