Treatment Development for Glucose Transporter Type I Deficiency Syndrome (G1D)
Status:
Completed
Trial end date:
2014-03-01
Target enrollment:
Participant gender:
Summary
The purpose of this trial is to determine if an alternative energy source will impact brain
metabolism in a disorder characterized by glucose metabolism failure in the brain.
The central hypothesis tested in this investigation is whether circumventing impaired glucose
metabolism is feasible, safe and potentially promising by supplying anaplerotic precursors
through metabolism of odd-carbon fatty acids that can enter the citric acid cycle (CAC)
through alternative metabolic pathways.