Treatment Efficacy of Local Anesthetic/Steroid Mixture Injection for Patients With Odynophonia

• Status: Not yet recruiting
• Trial end date: 2027-12-31
• Target enrollment: 0
• Participant gender: All

Summary

This is a double-blind, randomized, placebo-controlled trial. A total of 40 subjects will be randomized to experimental group (receiving bupivacaine/triamcinolone mixture) or control group (receiving saline injection). Two injections will be given one week apart. The primary outcome measure is the reduction in pain on the abbreviated McGill Pain Questionnaire (MPQ).

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of Texas Southwestern Medical Center
• Treatments: Bupivacaine; Triamcinolone Acetonide

Criteria

Inclusion Criteria:

• Patients who report pain associated with voicing and are diagnosed with odynophonia

Exclusion Criteria:

• • Vocal fold mobility or tissue abnormality

• history of jaw surgery/TMJ

• history of neck surgery or trauma

• Uncontrolled reflux. (patient's scoring on Reflux Symptom Index(RSI) is 13 or higher: Normative data suggests that a RSI of greater than or equal to 13 is clinically significant.)