Treatment Response of Maintenance Dose of Proton Pump Inhibitor in Patients With Nonerosive Gatroesophageal Reflux Disease

• Status: Completed
• Trial end date: 2019-10-18
• Target enrollment: 0
• Participant gender: All

Summary

For ERD(erosive reflux disease), which pathogenesis is mainly the acid reflux mechanism, primary treatment is therefore PPI. However, NERD(non-erosive reflux disease) is much more complex than ERD and there are more factors causing the typical symptoms. As a result, there is no consensus for the treatment of NERD besides using PPI similar to GERD(gastroesophageal reflux diseas). This study intent to evaluate the effect of PPI(Esomezol) on NERD patients and analyze the improvement of symptoms and the factors related to the result.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Yonsei University
• Treatments: Proton Pump Inhibitors

Criteria

Inclusion Criteria:

• Patient over 19 years old

• Patient with typical GERD symptom (heartburn or acid reflux more than once a week)

Exclusion Criteria:

• Patient who received EGD since the past 6 months, and diagnosed as GERD endoscopically

• Patient with active gastric/duodenal ulcer

• Patient who received esophagus, stomach or duodenum surgery

• Patient with hypersensitivity to esomezol®

• Patient with no achieved agreement on the study from the guardian or patient himself.