Treatment Response of Maintenance Dose of Proton Pump Inhibitor in Patients With Nonerosive Gatroesophageal Reflux Disease
Status:
Completed
Trial end date:
2019-10-18
Target enrollment:
Participant gender:
Summary
For ERD(erosive reflux disease), which pathogenesis is mainly the acid reflux mechanism,
primary treatment is therefore PPI. However, NERD(non-erosive reflux disease) is much more
complex than ERD and there are more factors causing the typical symptoms. As a result, there
is no consensus for the treatment of NERD besides using PPI similar to GERD(gastroesophageal
reflux diseas). This study intent to evaluate the effect of PPI(Esomezol) on NERD patients
and analyze the improvement of symptoms and the factors related to the result.