Treatment for Alcoholism and Post-Traumatic Stress Disorder (Naltrexone)
Status:
Completed
Trial end date:
2011-02-01
Target enrollment:
Participant gender:
Summary
This study will evaluate naltrexone and cognitive-behavioral therapy treatments for alcohol
dependence and post-traumatic stress disorder (PTSD). Subjects will be randomly assigned a
6-month treatment of either: 1) naltrexone alone, 2) naltrexone with PTSD psychosocial
therapy, 3) a placebo with PTSD psychosocial therapy, or 4) placebo alone. An enhanced
medication management intervention will accompany all treatment conditions. Follow-up
assessments will be completed at 9 and 12 months after treatment.
Phase:
Phase 4
Details
Lead Sponsor:
University of Pennsylvania
Collaborator:
National Institute on Alcohol Abuse and Alcoholism (NIAAA)