Overview

Treatment for Patients With Stage III or IV Non-Hodgkin Lymphoma

Status:
Completed
Trial end date:
2004-06-01
Target enrollment:
0
Participant gender:
All
Summary
The main purpose of this study is to determine if it is feasible to administer an intensified, multi-agent chemotherapy regimen for children with stage III and IV non-Hodgkin lymphoma and to find out what the toxicities are.
Phase:
N/A
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
St. Jude Children's Research Hospital
Treatments:
6-Mercaptopurine
Asparaginase
Cyclophosphamide
Cytarabine
Daunorubicin
Dexamethasone
Etoposide
Mercaptopurine
Methotrexate
Prednisone
Vincristine
Criteria
Inclusion Criteria:

- Stage III or IV Lymphoblastic Lymphoma

- One week or less of prior therapy, only to include steroids, vinca alkaloids, and
emergency radiation therapy to the mediastinum in those with severe respiratory.

Exclusion criteria:

- Patients with superior vena cava syndrome, significant compression of the trachea
requiring more than 40% oxygen or having significant dyspnea at normal activity