Treatment of Acute Pyelonephritis With Gram Negative Strains in Infants and Children Less Than 3 Years Old
Status:
Completed
Trial end date:
2009-02-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to demonstrate the equivalence of the therapeutic efficacy of
cefixime by mouth (PO) 10 days (d) and ceftriaxone intravenous route(IV) 4d followed by
cefixime PO 6d on renal scars 6 months after a first acute pyelonephritis episode.
The investigators hypothesize that treatment with cefixime PO will allow no more renal scars
than intravenous route (IV) treatment of pyelonephritis in infants and children less than 3
years old, 6 months after the first episode. If it is true, treatment will no longer need
hospitalisation and the advantages for children, families and the health system will be very
important.