Treatment of Asymptomatic Bacteriuria in Pregnancy

• Status: Terminated
• Trial end date: 2018-01-01
• Target enrollment: 0
• Participant gender: Female

Summary

This is a prospective randomized controlled day comparing the efficacy of three-day antimicrobial treatment of asymptomatic bacteriuria (ASB) in pregnancy to the standard seven-day treatment. Half the patients will receive 3-day treatment and the other half will receive 7 days of antibiotics.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Saint Joseph Mercy Health System
• Treatments: Cephalexin; Nitrofurantoin

Criteria

Inclusion Criteria:

• Pregnant women ≥ 18 years of age seeking prenatal care at the Academic Obstetrics and Gynecology Center at St. Joseph Mercy Hospital, Ann Arbor, Michigan

• Randomization will occur if the patient every has a urine culture demonstrating ≥10,000 cfu/ml of a pathogenic urinary tract organism

Exclusion Criteria:

• Symptomatic bacteriuria (cystitis or pyelonephritis) at the time of urine collection

• Previously treated bacteriuria in current pregnancy

• Past medical history of known congenital or acquired urinary tract anomaly or abnormality (i.e. pelvic kidney, single kidney, renal transplant)

• Any antibiotic use within the week prior to urine sampling

• Urine culture revealing growth of the following organisms: Lactobacillus, coagulase-negative staphylococcus