Treatment of Bipolar Mania in Older Adults

• Status: Completed
• Trial end date: 2011-08-01
• Target enrollment: 0
• Participant gender: All

Summary

This study will compare the benefits and side effects of lithium and divalproex in the treatment of older adults with bipolar mania.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Weill Medical College of Cornell University
• Collaborator: National Institute of Mental Health (NIMH)
• Treatments: Lithium Carbonate; Valproic Acid

Criteria

Inclusion Criteria:

• Diagnosis of DSM-IV Bipolar Disorder, Type I: current manic, mixed, or hypomanic episodes

Exclusion Criteria:

• Rapid cycling bipolar disorder

• History of substance abuse or dependence within last 3 months

• Diagnosis of schizophrenia or other chronic psychotic conditions

• Acute or unstable medical illness

• Documented intolerance to Lithium, Depakote, Risperidone, or Lorazepam

• Dementia

• Inability to communicate in English