Treatment of Clogged Tympanostomy Tubes: An Off-Label Use of Dornase Alfa (Pulmozyme®)
Status:
Completed
Trial end date:
2011-05-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to evaluate Pulmozyme® (dornase) as compared to a standard ear
drop Floxin® (ofloxicin) to dissolve clogged tubes. This study will monitor the use of the
new drug for any problems related to the medication. Patients are being asked to be in this
study because they had tubes placed for the treatment of chronic ear infection and the
tube(s) are now clogged. Clogged tubes are a common problem found in children with tubes.
This problem occasionally is improved with ear drops like Floxin®. However, it is frequently
not improved even after this standard ear drop treatment.