Treatment of Depression in Adults

• Status: Completed
• Trial end date: 2007-10-01
• Target enrollment: 0
• Participant gender: All

Summary

This study will determine how certain features of depressed individuals affect their responses to depression treatment.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of Pittsburgh
• Collaborator: National Institute of Mental Health (NIMH)
• Treatments: Citalopram; Dexetimide

Criteria

Inclusion Criteria:

• Diagnosis of Major depression

Exclusion Criteria:

• History of manic or hypomanic episodes

• History of schizophrenia or schizoaffective disorder

• Diagnosis of anorexia nervosa or bulimia nervosa

• Current psychosis

• Drug and/or alcohol dependence or abuse within 3 months prior to study entry. Participants with episodic abuse related to mood disorders will not be excluded.

• Diagnosis of antisocial personality disorder

• Diagnosis of organic affective syndrome and uncontrolled medical illness

• Pregnancy

• Require inpatient treatment for suicidal risk or psychosis

• History of an inability to tolerate any of the study treatments

• Currently receiving treatment with an effective antidepressant