Treatment of Diabetes in Patients With Systolic Heart Failure
Status:
Completed
Trial end date:
2018-09-01
Target enrollment:
Participant gender:
Summary
Investigator Initiated Study to study the effects of Canagliflozin 100 milligrams (mg) vs
Sitagliptin 100 mg on parameters of aerobic exercise capacity (peak oxygen consumption [VO2])
and ventilator efficiency (minute ventilation [VE]/carbon dioxide production [VCO2] slope) at
cardiopulmonary exercise test (CPET) after 12 weeks of active treatment (primary endpoints).
Blood pressure (BP), body water content, body composition, cardiac function, and diet will be
also measured (secondary endpoints).