Treatment of Drooling With Type A Botulinum Toxin in Children With Cerebral Palsy

• Status: Unknown status
• Trial end date: 2005-09-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to evaluate the effectiveness of botulinum toxin injection to treat drooling in children with cerebral palsy, and to find the most appropriate dosage, duration of effect and side effects.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: National Taiwan University Hospital
• Collaborator: National Science Council, Taiwan
• Treatments: abobotulinumtoxinA; Botulinum Toxins; Botulinum Toxins, Type A; incobotulinumtoxinA; onabotulinumtoxinA

Criteria

Inclusion Criteria:

• diagnosis of cerebral palsy

• severe drooling

• aged 6-21 yrs

• subjects (or their guardian) who are able to understand the requirements of the study and sign the informed consent form

Exclusion Criteria:

• age below 6 yrs or above 21 yrs

• known allergy or sensitivity to the study medication or its component

• diagnosis of myasthenia gravis, amyotrophic lateral sclerosis or any other disease that might interfere with neuromuscular function

• subjects who have prior surgery of the submandibular gland

• subjects who are receiving medication that affect drooling such as anticholinergic drug

• inability to give informed consent