Treatment of Early Childhood Caries Using Silver Diammine Fluoride and Sodium Fluoride Tricalciumphosphate and the Effects on Oral Health Related Quality of Life

• Status: Enrolling by invitation
• Trial end date: 2023-08-15
• Target enrollment: 0
• Participant gender: All

Summary

There is still a need for the assessment of different minimal intervention strategies and treatments focusing on the prevention and arrest of carious lesions of primary molars The evidence-based clinical practice guideline on non-restorative treatments for cavitated carious lesions advocate the use of silver diammine fluoride biannually for high caries risk patients

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Universiti Sains Malaysia
• Collaborators: 3M ESPE; SDI Limited
• Treatments: Fluorides; Listerine; Sodium Fluoride

Criteria

Inclusion criteria:

Children will be invited to participate in the trial if they fulfil the entire selection criteria as described below:

• 4 to 6 years-of-age

• Identification of one or more carious primary molars without involvement of the pulp confirmed by bitewing radiographs

• Up to three teeth per each participant will be selected for intervention

• Has normal salivary flow rate

• Does not consume medications regularly for any medical condition

• Has not or will not receive any fluoride therapy or relevant dental therapy from other dental sources within the last six months

Exclusion criteria:

Children will be excluded from the trial if they fulfil any of the following criteria:

• Presence of any pain, ulceration, fistula/sinus or an abscess

• Premature hypermobility of carious teeth which can be potentially included in the study

• History of allergy to any product containing silver compounds

• Siblings of the participants will not be allowed to participate to ensure any chance of ECOHIS duplication.