Treatment of Group A Beta Hemolytic Streptococcal Pharyngitis in Children in Low Resource Settings
Status:
Completed
Trial end date:
2003-04-01
Target enrollment:
Participant gender:
Summary
The purpose of this study was to compare the microbiological effects of two different
treatments: a single dose of intramuscular benzathine penicillin G (IM BPG) vs. a 10-day
daily dose of amoxicillin for the treatment of GABHS pharyngitis in children in low resource
settings. This study was a prospective multi-center randomized active control treatment
trial. The trial is a non-inferiority equivalence trial, to determine if amoxicillin
treatment is at least as effective as the currently given IM BPG treatment.
Phase:
N/A
Details
Lead Sponsor:
Johns Hopkins University
Collaborators:
Cairo University United States Agency for International Development (USAID) Universidade Federal do Rio de Janeiro University Hospital for Infectious Diseases, Croatia World Health Organization
Treatments:
Amoxicillin Anti-Bacterial Agents Antibiotics, Antitubercular beta-Lactams Penicillin G Penicillin G Benzathine Penicillin G Procaine Penicillins