Treatment of Knee Arthrosis With Platelet-derived Growth Factors vs. Hyaluronic Acid.

• Status: Completed
• Trial end date: 2014-07-01
• Target enrollment: 0
• Participant gender: All

Summary

Primary aim of this trial was to assess efficacy three intraarticular injections of platelet lysate when compared to hyaluronic acid. Additional objectives were to compare the treatment groups in terms of a number of functional scales and of number of adverse events.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: IRCCS Policlinico S. Matteo
• Treatments: Hyaluronic Acid; Mitogens

Criteria

Inclusion Criteria:

• grade II/III OA of the knee demonstrated at MRI17,18, according to Shahriaree Classification System - modified

• no previous OA treatment with local hyaluronic acid or steroid injections

• ife expectancy >1 year

• no ongoing pregnancy

• ability to understand and complete clinical and functional scales Lysholm, WOMAC, AKS, VAS

• written consent.