Overview

Treatment of Mantle Cell Lymphoma at Diagnosis for Patients Under 65 Years

Status:
Completed
Trial end date:
2008-12-01
Target enrollment:
Participant gender:
Summary
Phase II study to test in first line the VAD (Vincristine Adriablastine Dexamethasone) + C (Chlorambucil ) regimen associated to rituximab ( R-VAD + C ) in a cohort of young patients under 66 years with a mantle cell lymphoma and also the test the role of an in vivo marrow purge with rituximab before an autologous stem cell transplantation for the consolidation of the patients which fulfilled a response to 4 cycles of (R VAD + C) regimen.
Phase:
Phase 2
Details
Lead Sponsor:
French Innovative Leukemia Organisation
Collaborator:
Hoffmann-La Roche
Treatments:
Chlorambucil
Cyclophosphamide
Dexamethasone
Doxorubicin
Melphalan
Rituximab
Vincristine