Treatment of Non Promyelocytic Acute Myeloid Leukaemia on Elderly Patients by Low Dose Cytosar Plus Arsenic Trioxide

• Status: Completed
• Trial end date: 2008-02-01
• Target enrollment: 0
• Participant gender: All

Summary

Our purpose in this study is to explore the feasibility of treatment of non promyelocytic Acute myeloid leukaemia on elderly patients. We select ten patients with age further than 60 with comorbidity and treat by low dose cytosar subcutaneous plus arsenic trioxide for ten days in month. We will assess overall response rate and overall survival in end of one year.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Tehran University of Medical Sciences
• Treatments: Arsenic Trioxide; Cytarabine

Criteria

Inclusion Criteria:

• Elderly patients with non promyelocytic AML

• Performance status (ECOG) 3 or 4

Exclusion Criteria:

• Age <60 years

• Elevation of AST OR ALT more than ten times above normal

• Serum bilirubin above 5

• Cr level > 2