Overview

Treatment of Obsessive-Compulsive Disorder

Status:
Completed
Trial end date:
2003-07-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to find the best treatment for Tourette's Syndrome (TS)-spectrum obsessive-compulsive disorder (OCD), which includes symptoms of TS, e.g., repeated and involuntary body movements (tics). There are 2 parts to this study: In Part 1, patients are placed into 1 of 2 groups based on type of OCD, determined by medical history and family member interviews. In Part 2, patients are treated with fluvoxamine (FVX) for 8 weeks. If patients do not respond to FVX alone, either haloperidol or an inactive placebo will be added to the FVX regimen; patients will take this drug combination for 4 weeks. Patients will be monitored throughout the trial.
Phase:
Phase 4
Details
Lead Sponsor:
University of Florida
Collaborator:
National Institute of Mental Health (NIMH)
Treatments:
Antipsychotic Agents
Fluoxetine
Fluvoxamine
Haloperidol
Olanzapine
Serotonin
Serotonin Uptake Inhibitors