Overview

Treatment of Rett Syndrome With Recombinant Human IGF-1

Status:
Completed
Trial end date:
2016-11-01
Target enrollment:
Participant gender:
Summary
Investigators are recruiting children for a clinical trial using the medication recombinant human IGF-1 (a.k.a. mecasermin or INCRELEX) to see if it improves the health of children with Rett syndrome (RTT). While IGF-1 is approved by the Food & Drug Administration (FDA) for certain use in children, it is considered an investigational drug in this trial because it has not previously been used to treat RTT. Information from this study will help determine if IGF-1 effectively treats RTT but will not necessarily lead to FDA approval of IGF-1 as a treatment for RTT.
Phase:
Phase 2
Details
Lead Sponsor:
Boston Children's Hospital
Boston Children’s Hospital
Collaborator:
International Rett Syndrome Foundation
Treatments:
Insulin
Insulin, Globin Zinc
Mecasermin
Mitogens